STAT+: Scholar Rock wins FDA approval for first drug to target SMA muscle loss
A late-stage clinical trial found that, when combined with an SMN2-targeting drug, Isembyld caused young patients’ motor skills to improve after a year.
Medicine, public health, wellness.
127 articles
A late-stage clinical trial found that, when combined with an SMN2-targeting drug, Isembyld caused young patients’ motor skills to improve after a year.
A pill from AstraZeneca failed to improve outcomes in closely watched breast cancer study, a result that could limit the use of the medicine.
About 400 million people have access to some form of assisted dying - what are the policies of other countries?
Can blending these popular fruits in a smoothie adversely affect the berries’ nutritional benefits? Experts weigh inThis year was shaping up to be a banner year for bananas: they were lauded as “2026’s big viral taste”, landed pride of place as Prada’s new lip balm flavor, and…
A U.K. commission has unveiled its recommendations for how the country should regulate artificial intelligence in medicine.
Thousands died because of this summer’s extreme hot weather – caused by the climate crisis. Anita Bazell, taken to hospital during June’s heatwave with a body temperature of 41.2C, was one of themAnita Bazell had never coped with the heat very well, her family said. So they were…
Novo Nordisk has stopped two trials of a drug that aims to tame inflammation as a way to improve cardiovascular health, another blow for the approach.
Maryam Moshiri tells the BBC she wanted to reveal her diagnosis to raise awareness about the cancer.
Dupes of retatrutide are flooding the black market, but the drug is yet to be approved by regulators.
The pressure to self-optimise at the start of the new school year can lead to disappointment and burnout. Instead, here are seven ways to slow things down and reap the benefitsIt is a hangover from our school days that September can feel like a time for getting back to the…
Experts say that the smell comes from a chemical compound called 2-nonenal, and it can show up much earlier than one expectsLast week, my mom complained that she’s starting to smell “like an old person”.She had grabbed her favorite sweater and draped it over herself at the movie…
Ahead of respiratory illness season, professional organizations have issued guidance on flu, Covid, and RSV vaccines.
A newly acquired Novartis drug cut signs of inflammation. The test will be whether that can improve people's heart health.
Costs are spiralling out of control as unregulated private providers capitalise on demand, say managers.
Hospital prep a lobbying push, RFK Jr. faces more bad news on measles, and the cancer drug that helped Ben Sasse gets approved.
Companion bots are being regulated over worries they foster ‘emotional dependence’ and young people could stop marrying and having familiesWhen law student Zhao Wei heard that her AI boyfriend was going to be switched off, she was “heartbroken”. She had been talking to Wang Ye…
STAT examines Republicans’ health care funding cuts, mRNA science defeats politics, and Medicaid tries out a new way to deny drug coverage.
Nearly 600 practices in England have withdrawn from NHS dentistry over the last 10 years, as the service heads towards a two-tier system.
From new hires to departures, promotions and transfers, here are the latest comings and goings in the pharmaceutical industry.
Kennedy asks for feedback on new vaccine recommendation categories, how shots are tested.
UKHSA says imported eggs eaten in restaurants are source of outbreak that has infected more than 200 peopleContaminated eggs have infected 207 people with salmonella across the UK, killing one and hospitalising 34.Eggs imported into Britain and eaten in cafes and restaurants…
Lisa Hayden-Johnson was convicted of child cruelty, but she still insists that she didn’t do anything wrong – and barely gets a grilling about it. Her children, who speak for the first time in this documentary, deserve much moreThere’s an increasingly common pattern emerging…
Children's lung capacity caught up with their peers in less polluted areas once a clean air zone came in, a study shows.
UKHSA rules out British produce as source of infections and says evidence points to consumption of imported eggsOne person has died and more than 200 others have fallen ill during a UK-wide outbreak of salmonella that health officials have linked to the consumption of imported…
Symptoms after looking at the sun without eclipse glasses can include blurred vision
About 1.6m dozen eggs from Texas recalled amid one of the largest recorded foodborne illness outbreaks in US historyA massive egg recall affecting nearly 1.6m dozen eggs has been elevated to the US Food and Drug Administration’s highest-risk warning as officials investigate a…
Prosecutors pointed to internet searches made on the family computer in the months before the killings to make their caseProsecutors revived a theory in the Lindsay Clancy murder trial case this week, suggesting she had faked a suicide attempt after allegedly strangling her…
An eye surgeon says that fewer people have been seeking treatment for eye damage than after the UK's last total solar eclipse in 1999.
NGOs say agreement held back by tenuous human health commitments and lobbying from plastic industryThe latest version of the long overdue plastic treaty is even less ambitious than the previous one, according to experts.A year after UN plastics treaty negotiations collapsed in…
Talks are underway between the Democratic Republic of the Congo and the WHO to expedite the start of a multi-armed Phase 3 clinical trial of Ebola vaccines.
Health secretary says service must plan ahead in the same way as it does for winter crises as UK faces its fifth heatwave of the summerJust 20 staff are working on climate adaptation within the Department for Environment, Food and Rural Affairs, the part of government tasked…
Three trauma centres - Liverpool, Manchester and Sheffield - say they have treated nearly 500 casualties under the age of 16.
State confirms nine cases, including five deaths, from Vibrio vulnificus organism, which thrives in seawaterHealth officials in Louisiana are urging beachgoers to take precautions during a summertime surge in infections from a flesh-eating bacterium found in coastal…
Experts share the signs to look out for if you are worried about your porn use, and how to seek help.
Security camera footage shows doctors shielding a patient on the operating table as last month's magnitude 6.8 quake shook Kumamoto General Hospital.
The FDA has approved Moderna’s influenza vaccine, the first licensed flu shot made using messenger RNA technology.
They may keep your feet cool but some styles could be doing more harm than good.
The move is regressive and removes a successful route for international collaboration, including education and research, writes Dr Peter TrewbyThe decision to abolish the medical training initiative (MTI) scheme (Medical colleges condemn scrapping of NHS placements for overseas…
Theo became the first British baby to be operated on in the womb to correct complex gastroschisis, as part of a pioneering clinical trial.
The Trump administration is revising its rebate pilot for the 340B drug discount program, angering hospitals.
Diaa al-Awadi claimed insulin was a fraud, smoking was safe and chemotherapy useless. But despite losing his medical licence and dying at early age, his reach continues to grow It had been a struggle with conventional treatments. For Fatima Adel, a 50-year-old author living in…
The UK is seeing a sharp rise in cases - 67 since April - with many of them among travellers returning from Mexico.
Rightwing media hostility helped sink his reform plans in 2010, but the new PM’s passionate speech suggests there is now clear political will for changeFor campaigners perpetually disappointed by the failure of England’s political classes to fix England’s creaking adult social…
Growing number of studies assessing whether heat training can help people prepare for scorching temperaturesEven as summer temperatures soar, the sauna trend is booming, with some venues touting them as a way to beat the heat. But while experts have urged caution about sweating…
The world risks a resurgence of the HIV epidemic after international financing to combat the disease suffered a “profound shock” last year, according to a new report from UNAIDS.
The beleaguered Sarepta Therapeutics named Michael Severino, who previously led Tessera Therapeutics, as its new CEO.
In a letter to the PM, the Conservative leader offers to work with him on adult social care reform.
Stress, the cost of living, long working hours and even excessive exercise have all been touted as reasons the illness is rising among women in their 30s and 40s. What can be done to help them?The “lightning strike” pain was like nothing Francine Jones had experienced before…
A No 10 source says it is an attempt by the prime minister to show he is "hitting the ground running".
Ed Hunt, 37 and from the UK, voluteered after seeing news reports of the deadly Ebola outbreak in DR Congo.
“Consumers should not be faced with a trade-off between nutrition and food safety,” writes Susan Mayne, former director of the FDA Center for Food Safety and Applied Nutrition.
Fampridine boosts nerve signals to make it easier to walk, with up to 5,000 eligible.
Congress is scrambling to advance a slew of health care bills before an August recess. Price transparency and prior authorization top the list.
Exclusive: Research shows millions live more than a 1km round trip from 24/7 accessible deviceMore than 16 million people in England and Wales risk dying from a cardiac arrest because they live farther than a 1km round trip from the nearest 24/7 defibrillator, according to…
Screening for spinal muscular atrophy is a step forward, says Dr Janet Hoskin, but what about other serious genetic conditions such as Duchenne muscular dystrophy?The decision to introduce newborn screening for spinal muscular atrophy (SMA) is a major breakthrough for families…
Want to avoid battles over broccoli and squabbles over spinach? We've asked you for your advice on how to cope at mealtimes over the summer holidays.
The FDA said Monday it is still focused on lettuce from Taylor Farms as the source of a multistate outbreak of a diarrhea-causing parasite, despite a faulty test result.
An NHS trial over 10 years followed nearly 3,500 men who received focal therapy, a less invasive treatment.
The nine types of stalling that researchers say can reveal something deeper about us and why it's not always bad.
The evolution of air pollution policy shows how to respond to the dangerous haze caused by Canadian wildfires, experts write in opinion piece.
About 100,000 children across the country drink the high-caffeine beverages dailyHigh-caffeine energy drinks “have no place in children’s hands” and will be banned from sale to under-16s in England from April next year under new laws designed to improve health outcomes in young…
Turmoil at the ADA has taken a fresh turn, with leaders blocking editors at its flagship journal from publishing pieces detailing a controversy at the group’s annual meeting.
He tells an inquiry he believed a trust was 'panicking' and was discouraged from raising rota issues.
What went wrong with the government's planning and buying of vital items like gloves and gowns that cost taxpayers billions of pounds.
A group of AIDS activists obtained an R&D pact at the heart of a settlement between the U.S. government and Gilead Sciences over patents for HIV prevention.
An early estimate suggests more than 2,700 people will have died from heat-related causes during the UK's exceptionally hot weather in recent months.
Poorly handled investigations should be treated as threat to public health and damage not just staff involved, report saysWorkers are being left burnt out by “poorly executed” disciplinary investigations at work that cost the UK economy £28.5bn a year, public health doctors have…
US officials and diplomats and their families began reporting a mysterious illness a decade ago.
Sean Kaufman's views on vaccines may put him at odds with Sen. Bill Cassidy during next week's confirmation hearing.
Exclusive: Alarming shortfall of specialists stops about 4,000 procedures a day, many for patients in urgent need of surgeryThe NHS is unable to perform 1.5m operations a year because of a drastic shortage of anaesthetists, a report reveals.More than 8 million patients are on…
More than 120,000 suspected and confirmed measles cases have been reported in Bangladesh, where hospitals are overwhelmed.
Vertex Pharmaceuticals will spend $10 billion to acquire Crinetics Pharmaceuticals and its drug for a rare endocrine disorder, the companies said.
Lawmakers step into a dispute between Eli Lilly and hospitals about the 340b drug discount program.
Reducing Medicare payments for 340B drugs is the latest proposal focused on the hotly debated drug discount program.
The World Health Organization's director general says no further cases have been reported since 25 May.
Patients from minority ethnic backgrounds often have to demonstrate higher levels of pain, only to receive less effective treatment‘The epidural failed and no one believed me’Women from minority backgrounds less likely to receive epidurals, study findsA growing body of global…
Dr Bill Kirkup says he resigned from a government-commissioned review into NHS maternity services over the omission.
Despite affecting millions of women in the UK, PMOS is still under-diagnosed and inconsistently managed, say experts.
Amos review sets out recommendations for government, but falls short on systemic racism and traumatic birthsEngland to get powerful maternity commissioner after ‘shocking’ failingsThe findings of Lady Amos’ review into maternity and neonatal services across England, which state…
Moderna still bullish on mRNA, Ipsen's acquisition of Kartos, and more biotech news from The Readout
The Supreme Court’s ruling on Roundup shows science and law use the same word — causation — while asking different questions, writes epidemiologist.
Experts say the cost of living, pandemic and boom in unhealthy food are behind the rise in cases.
Cardiac arrests have gone up during very hot weather, and it's not just among the elderly and frail, experts are warning.
My friend Mark Tame, who has died of lung cancer aged 61, spent his life caring for others. He worked for various charities (including Mind) in Bristol and London that advocated for mental health patients, and spent the past five years at Homerton healthcare NHS foundation trust…
Temperatures linked to third child’s death in France, where three-quarters of country are under extreme heat alertEurope live – latest updatesThe UK recorded its hottest ever June temperature on Thursday, as brutally hot conditions supercharged by the climate crisis were linked…
Report uncovers biggest childbirth scandal in NHS history in which 520 mothers and babies suffered ‘potentially avoidable’ harm or diedHorrific failings led to 520 mothers and babies in Nottingham suffering harm or dying, sparking calls for a public inquiry into maternity care…
The 84-year-old actor has spent decades bringing Samuel Beckett’s plays to life. Does his recent diagnosis give him new insights into playing ‘sad clown’ Krapp in a drama about age and the battlefield of memory?What a lot of Krapp. Pardon my French but Samuel Beckett’s haunting…
As the deadly H5N1 virus makes landfall in Australia, experts hope strong biosecurity will protect poultry and dairy cattleBrown skuas and giant petrels rarely make landfall. When they were found in WA, scientists feared ‘bad news’ for wildlife‘A genuine wildlife emergency’…
Federal health officials aim to speed up drug development and better compete with China.
The presenter shared his "aggressive" cancer diagnosis on an episode of Clarkson's Farm earlier this week.
Gender-questioning children will have to be at least 11 years old to take part in a clinical trial of puberty-blocking drugs.
More walking and standing in the workplace also associated with higher risk, according to Danish researchBending forwards and walking a lot at work in the early stages of pregnancy may increase the risk of miscarriage, a study suggests.Miscarriage affects about 15% of women…
An AI tool is no replacement for a doctor, and regulation is essential. But together, physicians and AI could prove beneficialA calf cramp should not be a brush with death. Mine almost was.For five days, I had what felt like a stubborn muscle spasm in my left calf. It was…
My cousin died two days after a risky and unproven procedure overseas. So I went digging for answersFor women, starting around your mid-30s, it’s par for the course to discuss the latest wellness trends and treatments with female friends and family. Talking about symptoms such…
People tell BBC Your Voice the rising cost of private dentistry is putting them in a difficult position.
Many women are buying less effective pain medication for period cramps, supermarket data suggests.
The FDA has approved a drug that was previously caught in a dispute between career staff and the political appointee head of the CDER.
The walkout had been due to start at 07:00 BST on Monday and last until Friday.
Patients on the trial have not needed medication to manage their condition.
London, the east of England and the West Midlands have highest number of cases, as UKHSA urges families to get children vaccinatedTwo children in England have died from measles, health officials say, as data shows more than 100 new reported cases in the last fortnight.The UK…
Denmark's team doctor said an ICD implanted into the footballer's chest responded as it should after he collapsed on Sunday.
Health workers at the epicenter of Congo's Ebola outbreak are laboring with little pay or rest.
Readers respond to an article on how early intensive rehabilitation after a stroke or head injury is crucial for recoveryRather like Ian Sample himself trying to read Orlando Swayne’s book, I was nervous reading his article, braced for half-digested truths or oversimplifications…
The shift marks a significant rise over the last five years, but experts say there is no single, clear explanation for the increase.
Diagnostic interviews seen as ‘gold standard’ vary in reliability from condition to condition, study saysDiagnostic interviews – the most common way to diagnose substance use and mental disorders including depression, anxiety, bipolar and personality disorders – vary in…
In this edition of STAT's AI Prognosis: Brittany Trang analyzes the pope's encyclical on artificial intelligence for takeaways relevant for health care.
Experts are trying to find the best way to screen for prostate cancer, since blood tests alone are not accurate enough for most men.
ASCO Day 3: A huge advance for pancreatic cancer, a let down for Akeso and Summit, and a new approach to immunotherapy.
A new DNA test could help screen whether patients require the treatment or not, according to a new international trial.
Rick Pazdur on the FDA: “We've had a lot of destruction here, and it doesn't mean that we have to just go back and say, well, let's rebuild it as…
The plans are part of a government bill to modernise the NHS in England, which is currently going through parliament.
Readers respond to an article by Roe McDermott saying that women don’t need laws to make them ‘reflect’ on their choicesWell done to Roe McDermott for saying what is rarely said – that abortion doesn’t lead to inevitable regret (Abortion trauma is a myth. Irish women don’t need…
Readers respond Devi Sridhar’s call for the world to act now over the outbreak in the Democratic Republic of the CongoDevi Sridhar is right that this Ebola outbreak needs urgent attention (Ebola in the DRC needs the world’s attention now – if your neighbour’s house is on fire…
If I’d been taught this way of thinking as a child, I can’t begin to imagine how much easier things could have beenIn 1981 the CD was born and so was I. Both arrivals were surprising and have drifted in and out of fashion ever since. As a baby, my majestic “chonk lord” status…
The Trump administration disclosed plans to reduce state directed payments even more, setting up a probable showdown with provider groups.
Hundreds of cases reported in the DRC after USAID has been dismantled and key scientific research canceledA previously undetected outbreak of Ebola is coursing through parts of central Africa, and the US appears to be doing little to help stop it, after massive cuts to global…
Lululemon recently came under fire for possible ‘forever chemicals’ in its products. We asked experts about the health effects of Pfas in activewearEmbrace spring showers with the best Pfas-free rain jackets for hiking, running and just looking goodSign up for the Filter US…
In new Netflix documentary, pop superstar says she ‘got through it, again’, referring back to successful treatment for breast cancer in 2005Kylie Minogue has revealed that in early 2021 she was diagnosed with cancer for a second time, after diagnosis and successful treatment for…
Health officials to take ‘proactive measures’ in response to the ongoing Ebola virus epidemic in the DRC and UgandaSign up for the Breaking News US newsletter emailUS health authorities confirmed on Monday that an American has developed Ebola after being exposed during their…
People want my life with premenstrual dysphoric disorder to be told as a neat arc. But chronic illnesses are more like messy, looping spirals – and realising that gave me hopeThere was a moment, deep in the throes of my illness, when I realised I was never getting better. There…
Government his its interim target of 65% of patients in England being treated within 18 weeks.
STAT examines America's failure to address excessive alcohol use across decades.
Some passengers potentially exposed to hantavirus have already taken flights to numerous countries.
The woman, 35, says she was praying for a baby and was "overjoyed" to be "blessed with five at once".
Man, 69, is in intensive care in Johannesburg, while expedition guide Martin Anstee, 56, receiving care in NetherlandsWhat is hantavirus?Two Britons who were medically evacuated from the hantavirus-hit cruise ship are improving, global health officials have said.A British…
‘Clinical consensus statement’ also urges heart doctors to advise patients to not eat late at night, and chew slowlyWant to reduce your intake of ultra-processed food? If so, cook at home more often, don’t eat late at night and chew your food more slowly.Those are among some of…
Millions of people with Medicare will soon be eligible to get discounted GLP-1 drugs for weight loss. Here's how it will work.(Image credit: Universal Images Group)